ESPINHA BIFIDA OCULTA PDF

Ancillary intracranial sonographic findings: lemon sign : considered to have a strong association with spina bifida 2 banana sign : the appearance of the cerebellum wrapped around the medulla as part of a Chiari malformation Notably, closed and skin covered spinal lesions typically do not have any associated cranial abnormality. A normal cranial ultrasound therefore does not exclude a neural tube defect. Treatment and prognosis The overall prognosis is variable depending on the type and extent. For an isolated spina bifida, the recurrence risk range for future pregnancies is thought to be around 0. Maternal intake of folic acid in subsequent pregnancies may again reduce the risk significantly. References 1.

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Treatment[ edit ] There is no known cure for nerve damage caused by spina bifida. Standard treatment is surgery after delivery. This surgery aims to prevent further damage of the nervous tissue and to prevent infection; pediatric neurosurgeons operate to close the opening on the back.

The spinal cord and its nerve roots are put back inside the spine and covered with meninges. In addition, a shunt may be surgically installed to provide a continuous drain for the excess cerebrospinal fluid produced in the brain, as happens with hydrocephalus. Shunts most commonly drain into the abdomen or chest wall. Pregnancy[ edit ] Standard treatment is after delivery. There is tentative evidence about treatment for severe disease before delivery while the baby is inside the womb.

The first is open fetal surgery, where the uterus is opened and the spina bifida repair performed. The second is via fetoscopy. These techniques may be an option to standard therapy. Orthopedists monitor growth and development of bones, muscles, and joints. Neurosurgeons perform surgeries at birth and manage complications associated with tethered cord and hydrocephalus. Neurologists treat and evaluate nervous system issues, such as seizure disorders.

Urologists to address kidney, bladder, and bowel dysfunction — many will need to manage their urinary systems with a program of catheterization.

Bowel management programs aimed at improving elimination are also designed. Ophthalmologists evaluate and treat complications of the eyes. Orthotists design and customize various types of assistive technology, including braces, crutches, walkers, and wheelchairs to aid in mobility.

As a general rule, the higher the level of the spina bifida defect, the more severe the paralysis, but paralysis does not always occur. Thus, those with low levels may need only short leg braces, whereas those with higher levels do best with a wheelchair, and some may be able to walk unaided. Healthcare professionals working with adults may also be less knowledgeable about spina bifida because it is considered a childhood chronic health condition.

The transition itself should be gradual and flexible. A transition plan and aid in identifying adult healthcare professionals are also helpful to include in the transition process. Immigrants from Ireland have a higher incidence of spina bifida than do natives. The reported overall incidence of myelomeningocele in the British Isles was 2. Research[ edit ] — Fetal surgical techniques using animal models were first developed at the University of California, San Francisco by Michael R.

Harrison, N. Scott Adzick and research colleagues. The MMC-like defect was surgically created at 75 days of gestation term to days by a lumbo-sacral laminectomy. Approximately 3 weeks after creation of the defect a reversed latissimus dorsi flap was used to cover the exposed neural placode and the animals were delivered by cesarean section just prior term. Human MMC-like lesions with similar neurological deficit were found in the control newborn lambs.

In contrast, animals that underwent closure had near-normal neurological function and well-preserved cytoarchitecture of the covered spinal cord on histopathological examination. Despite mild paraparesis , they were able to stand, walk, perform demanding motor test and demonstrated no signs of incontinence.

Furthermore, sensory function of the hind limbs was present clinically and confirmed electrophysiologically. Further studies showed that this model, when combined with a lumbar spinal cord myelotomy leads to the hindbrain herniation characteristic of the Chiari II malformation and that in utero surgery restores normal hindbrain anatomy by stopping the leak of cerebrospinal fluid through the myelomeningocele lesion.

Four cases were performed before stopping the procedure - two of the four fetuses died. The exposed fetal spinal cord is covered in layers with surrounding fetal tissue at mid-gestation 19—25 weeks to protect it from further damage caused by prolonged exposure to amniotic fluid. Between and , Dr.

Fetal surgery after 25 weeks has not shown benefit in subsequent studies. This conclusion requires a value judgment on the relative value of fetal and maternal outcomes on which opinion is still divided. During pregnancy, all the fetuses in the trial had hindbrain herniation. However, at age 12 months, one-third 36 percent of the infants in the prenatal surgery group no longer had any evidence of hindbrain herniation, compared to only 4 percent in the postnatal surgery group.

This approach has been evaluated by independent authors of a controlled study which showed some benefit in survivors, [90] but others are more skeptical. In contrast, the initial punctures have a diameter of 1. As a result, thinning of the uterine wall or dehiscence which have been among the most worrisome and criticized complications after the open operative approach do not occur following minimally invasive fetoscopic closure of spina bifida aperta.

There is no need for chronic administration of tocolytic agents since postoperative uterine contractions are barely ever observed. In , two papers were published on fifty one patients. The main risk appears to be preterm labour, on average at about 33 weeks.

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